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Influenza A virus-IN-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Influenza Virus (23) Endogenous Metabolite (2) HIV (1) HPV (1) HSV (1) IFNAR (1) Interleukin Related (1) PROTACs (1) Reactive Oxygen Species (1) STING (1)
By Research Areas:	Cancer (1) Infection (21) Inflammation/Immunology (5) Metabolic Disease (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Influenza Virus Dengue virus Virus Protease AIM2 NEKs

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131179

**Influenza A virus-IN-1**	Influenza Virus	Infection
Influenza A virus-IN-1 is a dihydropyrrolidones derivative and is a potent inhibitor against wide subtypes of influenza A virus (IAV) with IC₅₀ values from 3.11 μM to 7.13 μM. Influenza A virus-IN-1 efficiently inhibits replication of IAV, up-regulates the expression of key antiviral cytokines IFN-β and antiviral protein MxA .

HY-N2216

Polygalasaponin XXXI OnjisaponIN F
Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection .

HY-145586

Onradivir

ZSP1273
Influenza Virus Infection

Onradivir is a potent anti-influenza virus agent .

Onradivir ZSP1273	Influenza Virus	Infection
Onradivir is a potent anti-influenza *virus* agent .

HY-143492

**Influenza virus-IN-1**	Influenza Virus	Inflammation/Immunology
Influenza virus-IN-1 (compound 14) is a potent **influenza A virus inhibitor with an EC₅₀ of 2.46 µM and CC₅₀** of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PA_N endonuclease with EC₅₀ of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities .

HY-145586A

Onradivir monohydrate

ZSP1273 monohydrate
Influenza Virus Infection

Onradivir monohydrate is a potent anti-influenza virus agent .

Onradivir monohydrate ZSP1273 monohydrate	Influenza Virus	Infection
Onradivir monohydrate is a potent anti-influenza *virus* agent .

HY-156288

Anti-Influenza agent 5	Influenza Virus	Infection
Anti-Influenza agent 5 (Compound IIB-2), chalcone-like derivative, is an influenza nuclear export inhibitor. Anti-Influenza agent 5 has inhibitory effects on oseltamivir-resistant strains. Anti-Influenza agent 5 can impede virus proliferation by blocking the export of influenza virus nucleoprotein .

HY-N0440

Germacrone

1 Publications Verification

Influenza Virus Infection

Germacrone is extracted from Rhizoma Curcuma. Germacrone inhibits influenza virus infection .

Germacrone 1 Publications Verification	Influenza Virus	Infection
Germacrone is extracted from Rhizoma Curcuma. Germacrone inhibits **influenza virus** infection .

HY-143493

Influenza virus-IN-2	Influenza Virus	Inflammation/Immunology
Influenza virus-IN-2 (compound 19) is a potent **influenza virus inhibitor with an EC₅₀ of 2.58 µM and CC₅₀** of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PA_N endonuclease with EC₅₀ of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities .

HY-P99699

Lesofavumab

MHAB5553A; RG70026
Influenza Virus Infection

Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .

Lesofavumab MHAB5553A; RG70026	Influenza Virus	Infection
Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .

HY-126136

ML303	Influenza Virus	Infection
ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC₉₀ = 155 nM), with an EC₅₀ of 0.7 μM for Influenza A virus H1N1 .

HY-155110

Antiviral agent 34	Influenza Virus	Infection
Antiviral agent 34 is a potent and orally active antiviral agent against *influenza* A and B subtypes with an EC₅₀ value of 0.8 nM for H1N1 proliferation. Antiviral agent 34 derivatives inhibited influenza virus proliferation by targeting influenza virus RNA-dependent RNA polymerase. Antiviral agent 34 can be used for influenza virus research .

HY-P0289

CEF3	Influenza Virus	Infection
CEF3 (SIIPSGPLK) corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle.

HY-137660

pppApG

Others Infection

pppApG is a starting product of both vRNA (viral RNA) and cRNA (complementary RNA) synthesis. pppApG can be used for influenza virus research .

pppApG	Others	Infection
pppApG is a starting product of both vRNA (viral RNA) and cRNA (complementary RNA) synthesis. pppApG can be used for influenza virus research .

HY-13318S

Oseltamivir acid-d3 GS 4071-d₃; Ro 64-0802-d₃; Oseltamivir carboxylate-d₃	Influenza Virus	Infection
Oseltamivir acid-d₃ is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

HY-147654

PROTAC Hemagglutinin Degrader-1	PROTACs Influenza Virus	Infection
PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent *PROTAC influenza* hemagglutinin (HA)** degrader with a median degradation concentration of 1.44 μM. PROTAC Hemagglutinin Degrader-1 shows broad-spectrum anti-influenza virus activity .

HY-P0313

CEF6

Influenza Virus Infection

CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.

CEF6	Influenza Virus	Infection
CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.

HY-W013794

Salcomine N,N′-Bis(salicylidene)ethylenediamINocobalt(II)	Others	Infection
Salcomine (N,N’-Bis(salicylidene)ethylenediaminocobalt II) is a carrier of O₂ and oxidation catalysts. Salcomine has anti-influenza virus activity .

HY-128965

N-Glycolylneuraminic acid NeuGc; GcNeu	Influenza Virus Endogenous Metabolite	Inflammation/Immunology
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding **influenza A viruses (IAVs)** .

HY-156048

Trifluoromethyl-tubercidin TFMT	Influenza Virus	Infection
Trifluoromethyl-tubercidin (TFMT) is a 2'-O-ribose methyltransferase 1 (MTr1) inhibitor through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication .

HY-131069A

MBX2329	Influenza Virus	Infection
MBX2329, a potent **influenza virus** inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC₉₀ of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains .

HY-134608

Cobalt protoporphyrin IX Co-PPIX	Reactive Oxygen Species Influenza Virus	Infection
Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) .

HY-N0224A

Goitrin (S)-GoitrIN; L-5-VINyl-2-thiooxazolidone	Influenza Virus	Metabolic Disease
Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .

HY-128965R

N-Glycolylneuraminic acid (Standard) NeuGc (Standard); GcNeu (Standard)	Influenza Virus Endogenous Metabolite	Inflammation/Immunology
N-Glycolylneuraminic acid (Standard) is the analytical standard of N-Glycolylneuraminic acid. This product is intended for research and analytical applications. N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding **influenza A viruses (IAVs)** .

HY-N2264

Wulignan A1
Wulignan A1 is isolated from the stems of Schisandra henryi. Wulignan A1 exhibits anti-influenza virus H1N1 and H1N1-TR (a Tamiflu agent resistant virus strain) activities .

HY-10964

Vadimezan Maximum Cited Publications 33 Publications Verification DMXAA; ASA-404	STING IFNAR Influenza Virus	Infection Cancer
Vadimezan (DMXAA; ASA-404), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan has anti-influenza virus H1N1-PR8 activities.

HY-107201

β-Cyclodextrin 1 Publications Verification Betadex	Influenza Virus	Infection
β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.

HY-107801

Inosine pranobex 1 Publications Verification Imunovir; Delimmun; GroprINosIN	Interleukin Related HSV HIV HPV	Infection Inflammation/Immunology
Inosine pranobex is an orally active immunomodulator. Inosine pranobex has broad-spectrum antiviral activity. Inosine pranobex inhibits human immunodeficiency virus (HIV), herpes simplex virus (HSV), vaccinia virus (VACV), human tumor virus (HPV), Cytomegalovirus, influenza virus (INFV), parainfluenza virus (PIV), and Epstein-Barr virus .

HY-125798

2,3-Dehydro-2-deoxy-N-acetylneuraminic acid 1 Publications Verification Neu5Ac2en; DANA	Influenza Virus	Infection
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC₅₀s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity .

CEF3	Influenza Virus	Infection
CEF3 (SIIPSGPLK) corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle.

CEF6	Influenza Virus	Infection
CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.

Lesofavumab MHAB5553A; RG70026	Influenza Virus	Infection
Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0440

Germacrone 1 Publications Verification	Infection Classification of Application Fields Terpenoids Sesquiterpenes Source classification Plants Curcuma longa Disease Research Fields Zingiberaceae	Influenza Virus
Germacrone is extracted from Rhizoma Curcuma. Germacrone inhibits **influenza virus** infection .

HY-128965

N-Glycolylneuraminic acid NeuGc; GcNeu	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Influenza Virus Endogenous Metabolite
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding **influenza A viruses (IAVs)** .

HY-P0289

CEF3	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Influenza Virus
CEF3 (SIIPSGPLK) corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle.

HY-N0224A

Goitrin (S)-GoitrIN; L-5-VINyl-2-thiooxazolidone	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease cruciferous vegetables Plants Brassicaceae Endogenous metabolite Disease Research Fields	Influenza Virus
Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .

HY-128965R

N-Glycolylneuraminic acid (Standard) NeuGc (Standard); GcNeu (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Influenza Virus Endogenous Metabolite
N-Glycolylneuraminic acid (Standard) is the analytical standard of N-Glycolylneuraminic acid. This product is intended for research and analytical applications. N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding **influenza A viruses (IAVs)** .

HY-107201

β-Cyclodextrin 1 Publications Verification Betadex	Infection Structural Classification Polysaccharides Microorganisms Classification of Application Fields Source classification Disease Research Fields Saccharides	Influenza Virus
β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.

Cat. No.	Product Name	Chemical Structure

HY-13318S

Oseltamivir acid-d3
Oseltamivir acid-d₃ is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

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Influenza A virus-IN-1

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

NaturalProducts

Isotope-Labeled Compounds

Natural
Products